Sunday, October 23, 2011

Hormone Replacement Therapy (HRT)





Until recently, hormone replacement therapy (HRT) is considered the best treatment option for women undergoing menopause. It is widely prescribed by doctors to treat various symptoms of menopause, but that all changed when some disturbing evidence on HRT began to emerge. In 2002, the U.S. government put an end to drug trials conducted Women's Health Initiative (WHI) on the use of hormone replacement therapy. During this test, it was found that HRT increases due to many diseases and disorders such as breast cancer, blood clots, stroke, endometrial cancer and disease srca.Rezultati were so dramatic that the negative HRT fell into disfavor and women more did not feel safe taking them.


Although the view HRT became negative due to women's Health Initiative study, it does not give a complete picture of HRT. Another study conducted at the same time as the WHI study found some problems with the WHI study, and left more questions than it answered. Since the WHI studied a group of women 50-79 years old with a mean age of 63 years this study probably reflects the long-term use of estrogen and not a reflection on the short HNL.WHI study also consisted of women who were more overweight than the U.S. population as a whole, so it would be more susceptible to cardiovascular problems even without the use of HRT so this also skews the results.


study of wisdom (Women International Study of long duration estrogen after menopause) began in the 1990s, was closed as a result of the negative results of the WHI study, but before it is breaking down the HRT by age group and long-term use and was getting better results regarding HRT. Wisdom was also looking at long-term use of estrogen alone and combined HRT with both estrogen and progesterone. Since the WISDOM study was never formally concluded no positive conclusions can be drawn from this study, but two questions still left unanswered whether the study were: 1) HRT can successfully use the term at the beginning of menopause? 2) Will different types of HRT treatments have the same negative results ?.


Risks associated with HRT:


• Breast Cancer
• endometrial cancer
• deep vein thrombosis
• Pulmonary embolism
• Strokes
• heart attack
• tinnitus
• Autoimmune disease complications


Obviously with so many risk factors, HRT is no longer as popular as it once was. It is still to be set today, but usually only for brief use 1:00 to 2:00 years for natural menopause. For women undergoing surgical menopause, HRT can be used for a longer duration, possibly even until natural menopause occurs.
Unfortunately, not much test data is available in various types of HRT are not currently available. Most clinical trials are conjugated horse estrogens (CEE), so most side effects attributable to HRT in conjunction with the CEE drugs. Bioidentical human estrogen has yet to be studied extensively and negative results in Central and Eastern Europe can not be applied to human bioidentical estrogen and other hormone treatments become available. Because bioidentical human estrogen, is becoming increasingly popular to do more tests, so that women can make informed choices.

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